The Southeastern Conference is expected to vote this week on whether to make its 2020 football season conference games only - an expected move that would follow other major conference leagues around the country.
But if that happens, Nicholls will lose its much-anticipated date at LSU, and also likely the payday attached to the game.
The SEC is voting today on the decision, but Sports Illustrated said last night that it is expected to pass.
League Presidents will have to approve the measure, but several athletic directors spoke in favor of the move yesterday at the SEC's virtual meetings.
The SEC would nix all of its non-conference games in favor of an SEC-only schedule, which would be expanded. Each team would play 10 conferences games this fall.
The additional two conference opponents would be based on a team's next two future "cross division" opponents.
For LSU, they would be adding Kentucky and Tennessee to its 2020 schedule.
But for Nicholls, the move would be a second lost non-conference game and one that comes with a 7-figure payday.
Colonels Athletic Director Jonathan Terrell said when he got the job that the LSU game was big for the university financially.
"We have to get that game played," Terrell said.
Without it, he said Nicholls would adjust and make a plan, but that it would be far more difficult.
The Colonels already had their home opener with Mississippi Valley State canceled when the SWAC canceled its fall sports.
The team is looking for a replacement. If the LSU non-conference games are lost, the Tigers would miss dates with UT-San Antonio, Texas, Rice and Nicholls.